In a world where humans and Youkai (demon) lived peacefully together, once people decide to change the time to do more day-time.
Opening theme song for Otome Yokai Zakuro is "Moon Signal" perfomed by Sphere. The Ending Themes are "Hatsukoi wa Zakuro-iro" by Mai Nakahara and Takahiro Sakurai; "Futari Shizuka" by Kana Hanazawa and Satoshi Hino and "Junjou Masquerade" by Aki Toyosaki, Yui Horie and Yuuki Kaji.